Guardiola said City had plenty of options, with Gabriel Jesus the only main striker fit and ready but Ilkay Gundogan and Raheem Sterling are able to slot into the role.
Sergio Aguero struck twice as Manchester City moved into second place in the Premier League, two points behind leaders Liverpool, with a 3-1 win at Bournemouth on Sunday. Just three weeks into the new season and last year's top two clubs are already perched at the top of the table.
Mario Balotelli headed the decisive goal as Italy emerged 2-1 winners over England in another high quality World Cup match in the Amazon jungle on Saturday, to gain a key early advantage in a Group D containing three former tournament winners.
Liverpool reached the Champions League semi-finals for the first time in 10 years as Mohamed Salah and Roberto Firmino struck decisive blows to secure a 2-1 win over Manchester City on Tuesday that completed a 5-1 aggregate victory.
City have 89 points, one more than rivals Liverpool, with both teams having three games to play -- and none of them against top six opponents.
Jose Mourinho's reshaped Manchester United destroyed Premier League champions Leicester City 4-1 with a performance that thrilled Old Trafford on Saturday and justified his decision to leave out Wayne Rooney. The shake-up seemed to liberate Paul Pogba who led the way with a polished display, heading his first goal for the club on 42 minutes and starting the clever move that led to Juan Mata firing home United's second after 37 minutes.
Iceland have already exceeded expectations by qualifying second in their group behind Hungary and will go into the game with nothing to lose and the whole world, beyond England, willing them on.
IMAGES from the English Premier League matches played on Wednesday.
Manchester City shook off the impact of a COVID outbreak in their ranks to outclass Chelsea 3-1 at Stamford Bridge
Images from the English Premier League matches played on Sunday
Manchester City must put a potentially ruinous fortnight behind them as they seek to reboot their faltering season with a big performance in their Champions League last-16, first leg trip to Dynamo Kiev on Wednesday.
Manchester City reached the League Cup final after recovering from a shaky start as Sergio Aguero's brilliant header sealed a 3-1 win over Everton in the semi-final second leg to clinch a 4-3 aggregate victory.
Manchester City's all-conquering season reached new peaks as Sergio Aguero became the club's all-time top scorer with a decisive goal in a thrilling 4-2 victory at Napoli that put them into the Champions League last 16 on Wednesday.
A summary of Saturday's action in the English Premier League.
There were a few nerves at the end but Liverpool set up a Champions League semi-final with Spain's Villarreal after Roberto Firmino scored twice in a 3-3 second-leg draw with Benfica on Wednesday to ensure a 6-4 aggregate win.
Of the 220 players who started for Premier League clubs at the weekend, only 73, or 33.2 per cent, were eligible to play for England.
Eight wins and a draw in their last nine games had seen Leicester emerge as the closest pursuers of runaway leaders Liverpool but they went down 3-1 at the Etihad despite taking an early lead through Jamie Vardy. Images from the English Premier League matches played on Saturday.
Another English football legend, Frank Lampard bid goodbye with a goal for Manchester City on final day of the season
"I want to reach the highest level possible as a player and I think the most important thing is that at the end of the season we can be happy and maybe have some titles," playmaker De Bruyne told the City website (www.mcfc.co.uk).
Manchester City secured a record 15th straight victory in all competitions with a 3-1 win at Championship side Swansea City in the FA Cup fifth round on Wednesday.
Liverpool opened up an eight-point lead at the top of the Premier League with an emphatic and hugely impressive 3-1 win over defending champions Manchester City.
England striker Daniel Sturridge celebrated his return after a five-month injury layoff when he came off the bench to score as Liverpool beat West Ham United 2-0 in the Premier League on Saturday.
Chelsea reached the League Cup final after Branislav Ivanovic's towering extra-time header secured a 1-0 victory over Liverpool in a rip-roaring semi-final second leg at an electric Stamford Bridge on Tuesday.
A round-up of Wednesday's action in the UEFA Champions League.
Liverpool continued their perfect start to the season to stay top of the Premier League after a goal in each half gave them a 2-1 victory over Tottenham Hotspur at Wembley on Saturday.
Phil Jagielka's stoppage-time thunderbolt earned Everton an unlikely 1-1 draw in the 223rd Merseyside derby on Saturday after Steven Gerrard's free kick appeared to have secured Liverpool a welcome victory.
Images from Sunday night's English Premier League matches.
Aymeric Laporte's late header sealed a deserved 1-0 victory over Tottenham Hotspur
Images from the English Premier League matches played on Sunday
Images from the English Premier League matches played on Saturday
England have lost to Germany in their last three knockout meetings at major tournaments
Images from the English Premier League matches on Saturday.
IMAGES from the EPL matches played on Saturday
After seven consecutive league defeats, and one point from the last 30 on offer, had plunged Villa into crisis and cost Tim Sherwood his job, the former European champions produced a gritty display to frustrate City.
It was not so much the maths, though Liverpool's nine-point advantage over defending champions City, with one point less over Leicester City and Chelsea, is a significant gap, especially as Juergen Klopp's side have lost one league game in 18 months.
The plucky underdogs were brought down to earth as Manchester City, Everton and Stoke City reached the League Cup semi-finals on Tuesday, ending the hopes of second-tier sides who felled fancied opponents in the last round.
There was the usual frenzy of last-minute deals as the English Premier League brought the curtain down on another bumper European transfer window in which Manchester City again flexed their financial muscle as the continent's top spenders.
Senegal international Mane faces a three-match suspension from domestic games, although he will be available for Liverpool's Champions League tie at home to Sevilla on Wednesday.
Atalanta's Josip Ilicic and Robin Gosens scored quickfire second-half goals to give them a comfortable 2-0 win over a toothless Liverpool
England's World Cup 2018 team, and remarkable similarities emerge between the XI expected to start the semi-final against Croatia
